Osteoporosis Society Alkalinefoodlist New Anti-cancer Drug: 200 Times More Active In Killing Tumor?

New Anti-cancer Drug: 200 Times More Active In Killing Tumor? - osteoporosis society alkalinefoodlist

Conducted on Science Daily (March 26, 2009) - A team of 24 researchers in the United States, Europe, Taiwan and Japan, by scientists at the University of Illinois, developed an anti-cancer agent, 200 times more active role in the destruction of tumor cells similar to drugs in recent clinical trials.

The study appears this week in the Journal of the American Chemical Society.

The new agent is in a class of drugs called bisphosphonates. These compounds were originally developed to treat osteoporosis and other bone diseases, but also discovered recently that strong immunosuppressive properties and promote cancer.

Drug developers have tried for years to drugs that inhibit the survival of the cell channels in tumor cells develop to involve Ras focused on a protein, given that almost one third of all human cancers than mutations in the gene, the cell-Ras signaling go wrong reasons. These efforts have had only limited success.

Bisphosphonates act on other enzymes, such as FPP and GGPP, which are known downstream of Ras in cell survival. Inhibition of these enzymesseems to be an effective strategy to kill cancer cells.

Used in combination with hormonal therapy in a recent clinical test is the bisphosphonate zoledronate drugs significantly reduced the recurrence of breast cancer in women before menopause with estrogen receptor-positive breast cancer. Similar results were previously reported in hormone-refractory prostate cancer. Quote
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When reading on cancer cells and is spoken of proteins and enzymes to make?

What does this mean (((drugs to cell survival in tumor cells through inhibiting)))